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Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X/antithrombin III' and Ligand = 'BDBM50310300'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X/antithrombin III


(Homo sapiens)
BDBM50310300
PNG
(CHEMBL606451 | N,N'-(ethane-1,2-diyl)bis(3,4-dihyd...)
Show SMILES Oc1ccc(cc1O)S(=O)(=O)NCCNS(=O)(=O)c1ccc(O)c(O)c1
Show InChI InChI=1S/C14H16N2O8S2/c17-11-3-1-9(7-13(11)19)25(21,22)15-5-6-16-26(23,24)10-2-4-12(18)14(20)8-10/h1-4,7-8,15-20H,5-6H2
PDB
MMDB

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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>3.00E+6n/an/an/an/an/an/a



Eastern Michigan University

Curated by ChEMBL


Assay Description
Inhibition of antithrombin-3 assessed as residual alpha-thrombin activity


Bioorg Med Chem Lett 20: 966-70 (2010)

More data for this
Ligand-Target Pair