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Found 1 Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM289842'
TargetCoagulation factor XI(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM289842(N-((2S)-1-(6-chloro-2-oxo-1,2-dihydrospiro[benzo[d...)
Affinity DataKi:  145nM ΔG°:  -39.0kJ/molepH: 7.4 T: 2°CAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent