Compile Data Set for Download or QSAR
Found 2 Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM50417503'
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences Inc

Curated by ChEMBL
LigandPNGBDBM50417503(GSK-561679 | GSK561679A | NBI-77860 | VERUCERFONT)
Show SMILES CC[C@H](Nc1cc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1C)c1nc(C)no1
Show InChI InChI=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14(4)26-28(19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/s1
Affinity DataKi:  6.31nMAssay Description:Antagonist activity at human recombinant CRF1 receptorMore data for this Ligand-Target Pair
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Neurocrine Biosciences Inc

Curated by ChEMBL
LigandPNGBDBM50417503(GSK-561679 | GSK561679A | NBI-77860 | VERUCERFONT)
Show SMILES CC[C@H](Nc1cc(C)nc2c(c(C)nn12)-c1ccc(OC)cc1C)c1nc(C)no1
Show InChI InChI=1S/C22H26N6O2/c1-7-18(22-24-15(5)27-30-22)25-19-11-13(3)23-21-20(14(4)26-28(19)21)17-9-8-16(29-6)10-12(17)2/h8-11,18,25H,7H2,1-6H3/t18-/m0/s1
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human recombinant CRF1 receptorMore data for this Ligand-Target Pair