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Found 2 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 26A1' and Ligand = 'BDBM50157724'
TargetCytochrome P450 26A1(Homo sapiens (Human))
The University Of Montana

Curated by ChEMBL
LigandPNGBDBM50157724(CHEMBL3787564 | US9963439, Compound B)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of microsomal fraction of human CYP26A1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 26A1(Homo sapiens (Human))
The University Of Montana

Curated by ChEMBL
LigandPNGBDBM50157724(CHEMBL3787564 | US9963439, Compound B)
Affinity DataIC50:  4.40E+3nMAssay Description:Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...More data for this Ligand-Target Pair
In DepthDetails US Patent