Affinity DataKi: 2.80E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide 4-methylhydroxylation after 60 mins by Dixon plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes assessed as tolbutamide 4'-hydroxylation after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP2C9 using tolbutamide as probeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Pooled human liver microsome suspension (20 mg/mL) was diluted with phosphate buffer to obtain a 5 mg/mL suspension. A solution of NADPH was prepared...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 μM by serial dilution with DMS...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+4nMAssay Description:Solutions of each test compound were separately prepared at
concentrations of 20000, 6000, 2000, 600, 200, and 60 uM by serial
dilution with DMSO:M...More data for this Ligand-Target Pair