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Found 3 Enz. Inhib. hit(s) with Target = 'Cytochrome P450 2D6' and Ligand = 'BDBM190405'
TargetCytochrome P450 2D6(Homo sapiens (Human))
Telormedix

US Patent
LigandPNGBDBM190405(US9180183, Quinidine)
Affinity DataIC50:  9nMAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Telormedix

US Patent
LigandPNGBDBM190405(US9180183, Quinidine)
Affinity DataIC50:  9nMT: 2°CAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Telormedix

US Patent
LigandPNGBDBM190405(US9180183, Quinidine)
Affinity DataIC50:  40nMpH: 7.4Assay Description:Specific aspects of the incubation conditions for each assay (e.g., protein concentration, incubation time, etc.) are defined in Walsky & Obach, 2004...More data for this Ligand-Target Pair
In DepthDetails US Patent