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Found 5 Enz. Inhib. hit(s) with Target = 'D(1A) dopamine receptor' and Ligand = 'BDBM50033116'
TargetD(1A) dopamine receptor(Sus scrofa)
Shaanxi University Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50033116((1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]SCH-23390 from porcine striatum dopamine D1 receptor incubated for 30 mins by radioligand competition binding assay based scintil...More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116((1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-...)
Affinity DataKi:  21nMAssay Description:Binding affinity against cloned human Dopamine receptor D1 using [125I]-SCH 23982 as radioligand transfected in HEK cellsMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116((1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-...)
Affinity DataKi:  30nMAssay Description:In vitro binding affinity against Dopamine receptor D1 like from rat caudate membrane using [125I]-SCH as radioligandMore data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116((1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-...)
Affinity DataEC50:  3nMAssay Description:Adenylate cyclase assay carried out in LTK cells transfected with human Dopamine receptor D1More data for this Ligand-Target Pair
TargetD(1A) dopamine receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50033116((1R,3S)-3-Adamantan-1-yl-1-aminomethyl-isochroman-...)
Affinity DataEC50:  5.10nMAssay Description:Effective concentration was determined for the adenylate cyclase activity in rat striatal tissue as a measure of Dopamine receptor D1 functional acti...More data for this Ligand-Target Pair