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Found 9 Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50020221'
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataKi:  0.660nMAssay Description:In vitro binding affinity of the compound is the ability to displace [3H]-spiperone from human Dopamine receptor D3 expressed in CHO-K1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from rat D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataKi:  1.36nMAssay Description:Displacement of [3H]spiperone from cloned dopamine D3 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Rattus norvegicus (Rat))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]spiperone from rat D3 dopamine receptor expressed in HEK293 cell membranes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataKi:  4.40nMAssay Description:Tested in vitro for the inhibition of [3H]-U-86,170 binding to Dopamine receptor D3, expressed in cloned CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataEC50:  0.140nMAssay Description:Activity at human dopamine D3 receptor expressed in AtT cells assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50020221((-)-5-hydroxy-2-(dipropylamino)tetralin | (-)-6-(d...)
Affinity DataEC50:  1.23nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed