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Found 8 Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM50058225'
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity for human Dopamine receptor D4 expressed in CHO K1 transfected cells using [3H]-Spiperone as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataKi:  8.71nMAssay Description:Binding affinity of compound towards human dopamine receptor D4 was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards cloned human Dopamine receptor D4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataKi:  17.0nMAssay Description:Binding affinity towards human dopamine receptor D4 expressed in CHO cells was determined by using [3H]thymidine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at human D4.4 receptor in HEK293 cells coexpressing Galphaqo5 by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataEC50:  17nMAssay Description:Agonist activation of human dopamine receptor stimulating mitogenesis in Dopamine receptor D4-transfected CHO pro-5 cells using [3H]-thymidine as rad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander-Universit£T Erlangen-N£Rnberg

Curated by ChEMBL
LigandPNGBDBM50058225(CHEMBL45244 | N-((4-(2-cyanophenyl)piperazin-1-yl)...)
Affinity DataEC50:  8.30nMAssay Description:Activity at human recombinant D4.4 receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed