BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DOPAMINE' and Ligand = 'BDBM50007428'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DOPAMINE


(RAT)
BDBM50007428
PNG
(7-[3-(4-Pyridin-2-yl-piperazin-1-yl)-propoxy]-chro...)
Show SMILES O=c1ccoc2cc(OCCCN3CCN(CC3)c3ccccn3)ccc12
Show InChI InChI=1S/C21H23N3O3/c25-19-7-15-27-20-16-17(5-6-18(19)20)26-14-3-9-23-10-12-24(13-11-23)21-4-1-2-8-22-21/h1-2,4-8,15-16H,3,9-14H2
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.17E+4n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
Compound was tested for its inhibitory effect on the binding profile in Dopamine receptor D1 using [3H]flupenthixol in rat brain.


J Med Chem 34: 248-56 (1991)


Article DOI: 10.1021/jm00105a039
BindingDB Entry DOI: 10.7270/Q20Z73WT
More data for this
Ligand-Target Pair