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Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM18229'
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

LigandPNGBDBM18229(5-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-...)
Affinity DataIC50:  0.0570nMAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Harvard Medical School

LigandPNGBDBM18229(5-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-...)
Affinity DataIC50:  0.0970nMpH: 7.4 T: 2°CAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

LigandPNGBDBM18229(5-[3-({2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-...)
Affinity DataIC50:  0.320nMAssay Description:Dihydrofolate reductase was assayed with no inhibitor and with a series of concentrations of inhibitors to allow for a range of inhibition from 10 to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed