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Found 2 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM18807'
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50: >5.40E+4nMAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18807(2-amino-6-methyl-5-[(4-nitrophenyl)sulfanyl]-3H,4H...)
Affinity DataIC50:  7.47E+6nMAssay Description:The inhibitory concentration of compound against Dihydrofolate reductases on rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed