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Found 4 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50049593'
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049593(6-Phenylaminomethyl-pyrido[3,2-d]pyrimidine-2,4-di...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against rat liver dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049593(6-Phenylaminomethyl-pyrido[3,2-d]pyrimidine-2,4-di...)
Affinity DataIC50:  260nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049593(6-Phenylaminomethyl-pyrido[3,2-d]pyrimidine-2,4-di...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Saccharomyces cerevisiae)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50049593(6-Phenylaminomethyl-pyrido[3,2-d]pyrimidine-2,4-di...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed