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Found 5 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50091145'
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against Lactobacillus casei Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against recombinant human (rh) Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)
Affinity DataIC50:  220nMpH: 7.4Assay Description:Inhibition of human DHFR at 30 degC under pH 7.4 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against human dihydrofolate reductase (DHFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50091145((S)-2-(4-(((2,4-diaminofuro[2,3-d]pyrimidin-5-yl)m...)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibitory concentration against Toxoplasma gondii Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB