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Found 6 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50158536'
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50158536((S)-2-{4-[3-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  7.00E+3nMpH: 7.4Assay Description:Inhibition of Escherichia coli dihydrofolate reductase at 37 degree C pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50158536((S)-2-{4-[3-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Escherichia coli DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50158536((S)-2-{4-[3-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50158536((S)-2-{4-[3-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  9.00E+3nMpH: 7.4Assay Description:Inhibition of human dihydrofolate reductase at 37 degree C pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50158536((S)-2-{4-[3-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  1.00E+4nMpH: 7.4Assay Description:Inhibition of Lactobacillus casei dihydrofolate reductase at 37 degree C pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50158536((S)-2-{4-[3-(2,4-Diamino-furo[2,3-d]pyrimidin-5-yl...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Lactobacillus casei DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed