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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor' and Ligand = 'BDBM50102319'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor/Serotonin 2 (5-HT2) receptor


(Rattus norvegicus (rat))
BDBM50102319
PNG
(11-(4-Methyl-piperazin-1-yl)-dibenzo[b,f][1,4]thia...)
Show SMILES CN1CCN(CC1)C1=Nc2ccc(O)cc2Sc2ccccc12
Show InChI InChI=1S/C18H19N3OS/c1-20-8-10-21(11-9-20)18-14-4-2-3-5-16(14)23-17-12-13(22)6-7-15(17)19-18/h2-7,12,22H,8-11H2,1H3
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 49n/an/an/an/an/an/a



AstraZeneca Pharmaceuticals LP

Curated by ChEMBL


Assay Description
Inhibition of spiropiperidone binding at dopamine receptor D2 of rat.


J Med Chem 44: 372-89 (2001)


Article DOI: 10.1021/jm000242+
BindingDB Entry DOI: 10.7270/Q2639P1N
More data for this
Ligand-Target Pair