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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)' and Ligand = 'BDBM50002164'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D2 receptor and Serotonin 2a receptor (D2 and 5HT2a)


(Rattus norvegicus (rat))
BDBM50002164
PNG
(3-[4-(4-Phenyl-piperidin-1-yl)-butyl]-1H-indole | ...)
Show SMILES C(CCc1c[nH]c2ccccc12)CN1CCC(CC1)c1ccccc1
Show InChI InChI=1S/C23H28N2/c1-2-8-19(9-3-1)20-13-16-25(17-14-20)15-7-6-10-21-18-24-23-12-5-4-11-22(21)23/h1-5,8-9,11-12,18,20,24H,6-7,10,13-17H2
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PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>100n/an/an/an/an/an/a



E. Merck Darmstadt

Curated by ChEMBL


Assay Description
Evaluated for its ability to displace tritiated receptor ligand in rat striatal membranes 3[H]spiperone, a dopamine antagonist


J Med Chem 35: 4020-6 (1992)


Article DOI: 10.1021/jm00100a006
BindingDB Entry DOI: 10.7270/Q2K0736G
More data for this
Ligand-Target Pair