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Found 3 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM50433903'
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50433903(CHEMBL2380586)
Affinity DataIC50:  10nMAssay Description:Inhibition of GST-fused full length human TTK compound pre-incubated for 15 mins prior ATP addition by MBP-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50433903(CHEMBL2380586)
Affinity DataIC50:  10nMAssay Description:Inhibition of MPS1 (unknown origin) using biotin-labeled AGAGLARHTDDEMTGYVA as substrate after 90 mins by DELFIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
University Health Network

Curated by ChEMBL
LigandPNGBDBM50433903(CHEMBL2380586)
Affinity DataIC50:  21nMAssay Description:Inhibition of FLAG-tagged MPS1 phosphorylation in human RERF-LC-AI Tet-off cells after 3 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed