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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual-specificity tyrosine-phosphorylation regulated kinase 1A' and Ligand = 'BDBM50399307'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual-specificity tyrosine-phosphorylation regulated kinase 1A


(Homo sapiens (Human))
BDBM50399307
PNG
(CHEMBL2180857)
Show SMILES Clc1nc(NC(=O)Nc2cccc3C(=O)N4CCCCC4c23)c(Cl)c(Cl)c1Cl
Show InChI InChI=1/C18H14Cl4N4O2/c19-12-13(20)15(22)24-16(14(12)21)25-18(28)23-9-5-3-4-8-11(9)10-6-1-2-7-26(10)17(8)27/h3-5,10H,1-2,6-7H2,(H2,23,24,25,28)
PDB
MMDB

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UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Universit£ d'Orl£ans

Curated by ChEMBL


Assay Description
Inhibition of human recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate and [gamma-33P]-ATP after 30 mins by...


J Med Chem 55: 9589-606 (2012)


Article DOI: 10.1021/jm3008536
BindingDB Entry DOI: 10.7270/Q28S4R2J
More data for this
Ligand-Target Pair