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Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM135166'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM135166(US8846657, 3.58)
Affinity DataIC50:  4nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 wi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM135166(US8846657, 3.58)
Affinity DataIC50:  4nMAssay Description:Methods: An HDM2 FRET assay was developed to assess the compounds' inhibitory activity towards binding of p53 protein. A truncated version of HDM2 wi...More data for this Ligand-Target Pair
In DepthDetails US Patent