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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'EBifunctional epoxide hydrolase 2' and Ligand = 'BDBM409007'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
EBifunctional epoxide hydrolase 2


(Homo sapiens (Human))
BDBM409007
PNG
(US10377744, Compound No. 28)
Show SMILES FC(F)(F)c1ccc(NC(=O)NC2CCN(CC2)C(=O)C2(CC2)C(F)(F)F)cc1
Show InChI InChI=1S/C18H19F6N3O2/c19-17(20,21)11-1-3-12(4-2-11)25-15(29)26-13-5-9-27(10-6-13)14(28)16(7-8-16)18(22,23)24/h1-4,13H,5-10H2,(H2,25,26,29)
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PC sid
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US Patent
0.0500n/an/an/an/an/an/an/an/a



Eicosis, LLC

US Patent


Assay Description
FRET assays to determine Ki for the compounds of Table I were carried out as described previously (Lee et al. Analytical Biochemistry 434 (2013) 259-...


US Patent US10377744 (2019)


BindingDB Entry DOI: 10.7270/Q2N3009K
More data for this
Ligand-Target Pair