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Found 4 Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50032172'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032172((S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propi...)
Affinity DataIC50:  15nMAssay Description:Inhibition of ET-1 binding to Endothelin A receptor in cultured rabbit renal artery vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032172((S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propi...)
Affinity DataIC50:  40nMAssay Description:Binding affinity against endothelin A receptor from rabbit renal vascular smooth musclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032172((S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propi...)
Affinity DataIC50:  58nMAssay Description:Inhibition of binding to Endothelin A receptor of rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50032172((S)-3-[(S)-2-((S)-2-Acetylamino-3,3-diphenyl-propi...)
Affinity DataIC50:  70nMAssay Description:Inhibition of ET-1 stimulated arachidonic acid release in rabbit renal vascular smooth muscle cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed