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Found 1 hit Enz. Inhib. hit(s) with Target = 'Endothelin-converting enzyme 2 (ECE-2)' and Ligand = 'BDBM92500'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelin-converting enzyme 2 (ECE-2)


(Homo sapiens (Human))
BDBM92500
PNG
(Kelatorphan)
Show SMILES C[C@H](NC(=O)[C@@H](CC(=O)NO)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C14H18N2O5/c1-9(14(19)20)15-13(18)11(8-12(17)16-21)7-10-5-3-2-4-6-10/h2-6,9,11,21H,7-8H2,1H3,(H,15,18)(H,16,17)(H,19,20)/t9-,11+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Similars

Article
PubMed
195n/a 380n/an/an/an/an/an/a



Pharmaleads



Assay Description
Inhibitory assay against ECE-2.


J Biol Chem 285: 34390-400 (2010)


Article DOI: 10.1074/jbc.M110.120576
BindingDB Entry DOI: 10.7270/Q29P307K
More data for this
Ligand-Target Pair