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Found 7 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM170514'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM170514(US9085540, 54)
Affinity DataIC50:  1.70nMAssay Description:The phosphorylation activity on the peptide substrate of EGFR was investigated using LabChip (trademark) Systems (Caliper Life Sciences, Inc.). For t...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM170514(US9085540, 54)
Affinity DataIC50:  4.5nMAssay Description:The phosphorylation activity on the peptide substrate of EGFR was investigated using LabChip (trademark) Systems (Caliper Life Sciences, Inc.). For t...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM170514(US9085540, 54)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFR L858R/T790M double mutant in human NCI-H1975 cells assessed as suppression of cell proliferationMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM170514(US9085540, 54)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFR Del ex19 mutant in human HCC827 cells assessed as suppression of cell proliferationMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM170514(US9085540, 54)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFR Del ex19 mutant in human PC9 cells assessed as suppression of cell proliferationMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM170514(US9085540, 54)
Affinity DataIC50:  8nMAssay Description:Inhibition of EGFR Del ex19/T790M double mutant in human PC9 cells assessed as suppression of cell proliferationMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM170514(US9085540, 54)
Affinity DataIC50:  230nMAssay Description:Inhibition of wild type EGFR in human NCI-H1666 cells assessed as suppression of cell proliferationMore data for this Ligand-Target Pair