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Found 4 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50171514'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50:  0.0700nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50:  15nMAssay Description:Inhibition of HER1 kinase in intact DHER14 cells; Range = 5-15 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 25-50 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hadassah Hebrew University

Curated by ChEMBL
LigandPNGBDBM50171514(2-Chloro-N-[4-(4,5-dichloro-2-fluoro-phenylamino)-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of EGF Receptor autophosphorylation in A431 cell lysate; Range = 5-25 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed