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Found 1 hit Enz. Inhib. hit(s) with Target = 'Falcipain-2' and Ligand = 'BDBM50339267'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Falcipain-2


(Plasmodium falciparum)
BDBM50339267
PNG
((Z/E)-3-((3-(7-chloroquinolin-4-ylamino)propylamin...)
Show SMILES Clc1ccc2c(NCCCN=CC3C(=O)Nc4ccccc34)ccnc2c1
Show InChI InChI=1/C21H19ClN4O/c22-14-6-7-16-18(8-11-25-20(16)12-14)24-10-3-9-23-13-17-15-4-1-2-5-19(15)26-21(17)27/h1-2,4-8,11-13,17H,3,9-10H2,(H,24,25)(H,26,27)/b23-13+
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of Lisbon

Curated by ChEMBL


Assay Description
Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...


Eur J Med Chem 46: 927-33 (2011)


Article DOI: 10.1016/j.ejmech.2011.01.008
BindingDB Entry DOI: 10.7270/Q2ZC8345
More data for this
Ligand-Target Pair