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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 2' and Ligand = 'BDBM130827'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 2


(Homo sapiens (Human))
BDBM130827
PNG
(US8829199, 68)
Show SMILES CCCCc1ccc2cc([nH]c2c1)C(=O)c1cnn(c1N)-c1ccc2nc(C)nc2c1
Show InChI InChI=1S/C24H24N6O/c1-3-4-5-15-6-7-16-11-22(29-20(16)10-15)23(31)18-13-26-30(24(18)25)17-8-9-19-21(12-17)28-14(2)27-19/h6-13,29H,3-5,25H2,1-2H3,(H,27,28)
PDB
MMDB

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KEGG

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PC cid
PC sid
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US Patent
n/an/a 200n/an/an/an/an/an/a



Chugai Seiyaku Kabushiki Kaisha; F. Hoffmann-La Roche AG

US Patent


Assay Description
The FGFR2-inhibiting activity was measured based on the activity to inhibit phosphorylation of the biotinylated peptide EGPWLEEEEEAYGWMDF by the huma...


US Patent US8829199 (2014)


BindingDB Entry DOI: 10.7270/Q26T0KB8
More data for this
Ligand-Target Pair