Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 (Homo sapiens (Human)) | BDBM50355393![]() (CHEMBL1834657 | US9434697, BGJ398) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | 2.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of VEGFR3 juxtamembrane domain-mediated proliferation of mouse BAF3 cells transformed with TEL-Kinase construct | J Med Chem 54: 7066-83 (2011) | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 (Homo sapiens (human)) | BDBM50355393![]() (CHEMBL1834657 | US9434697, BGJ398) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars AffyNet ![]() | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institute for BioMedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant FAK | J Med Chem 54: 7066-83 (2011) | |||||||||||
More data for this Ligand-Target Pair |