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Found 2 hits Enz. Inhib. hit(s) with Target = 'Glucocerebrosidase (Acid beta-Glucosidase)' and Ligand = 'BDBM108423'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocerebrosidase (Acid beta-Glucosidase)


(Homo sapiens (human))
BDBM108423
PNG
(US8604206, (3R,4R,5R)-5((S)-hydroxy(phenyl)methyl)...)
Show SMILES O[C@@H]([C@H]1CNC[C@@H](O)[C@@H]1O)c1ccccc1
Show InChI InChI=1S/C12H17NO3/c14-10-7-13-6-9(12(10)16)11(15)8-4-2-1-3-5-8/h1-5,9-16H,6-7H2/t9-,10-,11-,12-/m1/s1
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
8.90n/a 17n/an/an/an/a7.0n/a



Amicus Therapeutics, Inc.

US Patent


Assay Description
The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...


Citation and Details
More data for this
Ligand-Target Pair
Glucocerebrosidase (Acid beta-Glucosidase)


(Homo sapiens (human))
BDBM108423
PNG
(US8604206, (3R,4R,5R)-5((S)-hydroxy(phenyl)methyl)...)
Show SMILES O[C@@H]([C@H]1CNC[C@@H](O)[C@@H]1O)c1ccccc1
Show InChI InChI=1S/C12H17NO3/c14-10-7-13-6-9(12(10)16)11(15)8-4-2-1-3-5-8/h1-5,9-16H,6-7H2/t9-,10-,11-,12-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
1.36E+3n/a 3.29E+3n/an/an/an/a5.2n/a



Amicus Therapeutics, Inc.

US Patent


Assay Description
The enzyme inhibition assays used monitored the ability of a test compound to bind and prevent the hydrolysis of a fluorogenic substrate in a concent...


Citation and Details
More data for this
Ligand-Target Pair