Compile Data Set for Download or QSAR
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Found 2 Enz. Inhib. hit(s) with Target = 'Glucocorticoid receptor' and Ligand = 'BDBM50249141'
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50249141(15-methyl-N-(4-methyl-1,3-thiazol-2-yl)tetracyclo[...)
Affinity DataKi:  8.70nMAssay Description:Displacement of FITC-dexamethasone from human recombinant glucocorticoid receptor alpha by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50249141(15-methyl-N-(4-methyl-1,3-thiazol-2-yl)tetracyclo[...)
Affinity DataEC50: >5.00E+3nMAssay Description:Transrepression activity at GR in PMA-stimulated human A549 cells assessed as inhibition of AP1 response element-induced luciferase reporter gene act...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed