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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic AMPA' and Ligand = 'BDBM50059674'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutamate receptor ionotropic AMPA


(Homo sapiens (Human))
BDBM50059674
PNG
((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...)
Show SMILES Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O
Show InChI InChI=1S/C8H10N6O4/c1-14-6(10-12-13-14)5-3(7(15)11-18-5)2-4(9)8(16)17/h4H,2,9H2,1H3,(H,11,15)(H,16,17)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a>3.00E+6n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at GluR3 expressed in HEK293 cells by Fluo-4/Ca2+ assay


J Med Chem 50: 4177-85 (2007)


Article DOI: 10.1021/jm070532r
BindingDB Entry DOI: 10.7270/Q29P32F3
More data for this
Ligand-Target Pair
Glutamate receptor ionotropic AMPA


(Homo sapiens (Human))
BDBM50059674
PNG
((RS)-2-amino-3-[3-hydroxy-5-(1-methyl-2H-5-tetrazo...)
Show SMILES Cn1nnnc1-c1o[nH]c(=O)c1CC(N)C(O)=O
Show InChI InChI=1S/C8H10N6O4/c1-14-6(10-12-13-14)5-3(7(15)11-18-5)2-4(9)8(16)17/h4H,2,9H2,1H3,(H,11,15)(H,16,17)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/an/an/a 3.00E+6n/an/an/an/a



University of Copenhagen

Curated by ChEMBL


Assay Description
Agonist activity at GluR4 expressed in HEK293 cells by Fluo-4/Ca2+ assay


J Med Chem 50: 4177-85 (2007)


Article DOI: 10.1021/jm070532r
BindingDB Entry DOI: 10.7270/Q29P32F3
More data for this
Ligand-Target Pair