BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM164403'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM164403
PNG
(US9066954, 17)
Show SMILES COc1ccc2c(OCc3nnc4ccc(nn34)-c3ccc(-c4nc(C)no4)c(Cl)c3)ccnc2c1
Show InChI InChI=1S/C25H18ClN7O3/c1-14-28-25(36-32-14)17-5-3-15(11-19(17)26)20-7-8-23-29-30-24(33(23)31-20)13-35-22-9-10-27-21-12-16(34-2)4-6-18(21)22/h3-12H,13H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
9.30 -46.1n/an/an/an/an/a8.027



Amgen Inc.

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...


US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair