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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Hepatocyte growth factor receptor' and Ligand = 'BDBM164424'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))
BDBM164424
PNG
(US9066954, 62)
Show SMILES COc1cnc2c(OCc3cnc4ccc(nn34)-c3cc(F)c(F)c(F)c3)ccnc2c1
Show InChI InChI=1S/C22H14F3N5O2/c1-31-14-8-18-22(28-10-14)19(4-5-26-18)32-11-13-9-27-20-3-2-17(29-30(13)20)12-6-15(23)21(25)16(24)7-12/h2-10H,11H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
1.70 -50.4n/an/an/an/an/a8.027



Amgen Inc.

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...


US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair