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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'High affinity nerve growth factor receptor' and Ligand = 'BDBM134706'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM134706
PNG
(US8846698, 169)
Show SMILES Cn1cc(C(=O)c2cncc(NC(=O)Cc3ccccc3C(F)(F)F)c2)c2cncnc12
Show InChI InChI=1S/C22H16F3N5O2/c1-30-11-17(16-10-27-12-28-21(16)30)20(32)14-6-15(9-26-8-14)29-19(31)7-13-4-2-3-5-18(13)22(23,24)25/h2-6,8-12H,7H2,1H3,(H,29,31)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.10E+3n/an/an/an/an/an/a



Pfizer Inc

US Patent


Assay Description
Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so...


US Patent US8846698 (2014)


BindingDB Entry DOI: 10.7270/Q2F47MTW
More data for this
Ligand-Target Pair