BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histamine H1 receptor' and Ligand = 'BDBM50007458'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H1 receptor


(RAT)
BDBM50007458
PNG
(1-[4-(9-Fluoro-5,6-dihydro-benzo[5,6]cyclohepta[1,...)
Show SMILES CC(=O)N1CCC(CC1)=C1c2cc(F)ccc2CCc2cccnc12
Show InChI InChI=1S/C21H21FN2O/c1-14(25)24-11-8-16(9-12-24)20-19-13-18(22)7-6-15(19)4-5-17-3-2-10-23-21(17)20/h2-3,6-7,10,13H,4-5,8-9,11-12H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
2.90E+3n/an/an/an/an/an/an/an/a



Schering-Plough Corporation

Curated by ChEMBL


Assay Description
Binding affinity to histamine H1 receptor in rat brain membranes was evaluated using [3H]-pyrilamine as radioligand


J Med Chem 34: 457-61 (1991)


Article DOI: 10.1021/jm00105a069
BindingDB Entry DOI: 10.7270/Q2BV7FK0
More data for this
Ligand-Target Pair