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Found 4 Enz. Inhib. hit(s) with Target = 'Histamine H2 receptor' and Ligand = 'BDBM50275884'
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50275884(CHEMBL471413 | N1-(3,3-Diphenylpropanoyl)-N2-[3-(1...)
Affinity DataEC50:  78nMAssay Description:Activity at human recombinant histamine H2 receptor-Gsalpha fusion protein expressed in Sf9 cells by steady-state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50275884(CHEMBL471413 | N1-(3,3-Diphenylpropanoyl)-N2-[3-(1...)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human histamine H2 receptor expressed in Sf9 cells coexpressing Gsalphas by steady-state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50275884(CHEMBL471413 | N1-(3,3-Diphenylpropanoyl)-N2-[3-(1...)
Affinity DataEC50:  28.2nMAssay Description:Agonist activity at histamine H2 receptor in guinea pig spontaneously beating right atrium assessed as positive chronotropic activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H2 receptor(Cavia porcellus (domestic guinea pig))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50275884(CHEMBL471413 | N1-(3,3-Diphenylpropanoyl)-N2-[3-(1...)
Affinity DataEC50:  6nMAssay Description:Activity at guinea pig recombinant histamine H2 receptor-Gsalpha fusion protein expressed in Sf9 cells by steady-state GTPase activity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed