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Found 2 Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM26394'
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM26394(2,4-diamino-5,6-disubstituted pyrimidine, 8 | 4-(p...)
Affinity DataKi:  4.80nM ΔG°:  -47.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26394(2,4-diamino-5,6-disubstituted pyrimidine, 8 | 4-(p...)
Affinity DataKi:  13nM ΔG°:  -45.0kJ/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed