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Found 5 Enz. Inhib. hit(s) with Target = 'Histamine H4 receptor' and Ligand = 'BDBM50412494'
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50412494(CHEMBL452847 | VUF-10497)
Affinity DataKi:  7.59nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50412494(CHEMBL452847 | VUF-10497)
Affinity DataKi:  7.59nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Rattus norvegicus (rat))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50412494(CHEMBL452847 | VUF-10497)
Affinity DataKi:  15.8nMAssay Description:Binding affinity to rat histamine H4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50412494(CHEMBL452847 | VUF-10497)
Affinity DataKi:  43nMAssay Description:Displacement of [3H]histamine from human histamine 4 receptor expressed in Sf9 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50412494(CHEMBL452847 | VUF-10497)
Affinity DataIC50:  69.2nMAssay Description:Inverse agonist activity at human histamine H4 receptor expressed in HEK293T cells by CRE-beta-galactosidase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed