BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Histone chaperone ASF1A' and Ligand = 'BDBM50101689'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone chaperone ASF1A


(Homo sapiens)
BDBM50101689
PNG
(CHEMBL3394909)
Show SMILES COc1cc(\C=N\NC(=O)c2ccc(NC(=O)c3ccccc3)cc2)ccc1O
Show InChI InChI=1S/C22H19N3O4/c1-29-20-13-15(7-12-19(20)26)14-23-25-22(28)17-8-10-18(11-9-17)24-21(27)16-5-3-2-4-6-16/h2-14,26H,1H3,(H,24,27)(H,25,28)/b23-14+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Colorado State University

Curated by ChEMBL


Assay Description
Inhibition of His-tagged human Asf1a binding with H3/H4 assessed as fluorescence intensity after 30 mins by ALPHA assay


Bioorg Med Chem Lett 25: 963-8 (2015)


Article DOI: 10.1016/j.bmcl.2014.11.067
BindingDB Entry DOI: 10.7270/Q2VM4F0G
More data for this
Ligand-Target Pair