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Found 24 Enz. Inhib. hit(s) with Target = 'Histone deacetylase' and Ligand = 'BDBM50005711'
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataKi:  504nMAssay Description:Inhibition of HDAC in human Hela cells nuclear extracts by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extract using BML-KI104 Fluor de Lys as substrate by fluorescence-based assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  3nMAssay Description:Inhibition of HDAC in human HeLa cells using Ac-Arg-Gly-Lys(Ac)-AMC as fluorescent substrate after 20 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  3.40nMAssay Description:Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  4.60nMAssay Description:Inhibitory activity against partially purified histone deacetylase of human leukemia K562 cells.More data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  5nMAssay Description:Inhibition of histone deacetylase (HDAC) activity in HeLa cell nuclear extractMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  5nMAssay Description:Inhibition of HDAC in human HeLa cell nuclear extracts after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human HDAC in HeLa cells by flour de lys assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of HDAC in human HeLa cell extract after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Rattus norvegicus)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against histone deacetylase (HDAC)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human HDAC after 30 minsMore data for this Ligand-Target Pair
TargetHistone deacetylase(Rattus norvegicus)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 12aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Rattus norvegicus)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  26nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Fluor de Lys as substrate incubated for 20 mins by fluorometric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against histone deacetylase (HDAC) enzyme obtained from H1299 human lung carcinoma cell lysatesMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  26nMAssay Description:Concentration required to inhibit human Histone deacetylase (HDAC) enzyme by 50%More data for this Ligand-Target Pair
TargetHistone deacetylase(Rattus norvegicus)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against rat liver histone deacetylase (HDAC) with substrate 5aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human HDAC in human HeLa cell nuclear extract after 15 mins by colorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  53nMAssay Description:Inhibitory activity against Histone deacetylase (HDAC) from SNU-16 (human gastric adenocarcinoma) cellsMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  55nMAssay Description:Inhibitory concentration against human histone deacetylase (HDAC) from HeLa cells with substrate 5aMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hacettepe University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  100nMAssay Description:Concentration required to inhibit the partially purified HDAC enzyme by 50% obtained from H1299 cell lysateMore data for this Ligand-Target Pair
TargetHistone deacetylase(Rattus norvegicus)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition concentration required to inhibit rat liver histone deacetylase (HDAC) in the presence of compound 5e as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed