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Found 3 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 1' and Ligand = 'BDBM50276074'
TargetHistone deacetylase 1(Homo sapiens (Human))
Genentech

LigandPNGBDBM50276074(CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...)
Affinity DataIC50:  7.93nMpH: 7.5Assay Description:Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Genentech

LigandPNGBDBM50276074(CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human HDAC1 expressed in mammalian cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Genentech

LigandPNGBDBM50276074(CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...)
Affinity DataKd:  24.6nMpH: 8.0Assay Description:Specifically, the experiments were conducted in black 384-well polypropylene plates (Corning Glass) in a 15-ul reaction volume consisting of 11 nM HD...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed