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Found 5 Enz. Inhib. hit(s) with Target = 'Histone deacetylase 3' and Ligand = 'BDBM178100'
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)
Affinity DataKi:  29nM ΔG°:  -43.0kJ/mole IC50:  64nMpH: 7.4 T: 2°CAssay Description:Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)
Affinity DataIC50:  64nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)
Affinity DataIC50:  64nMAssay Description:Inhibition of recombinant human full length HDAC3 using FAM-labeled acetylated peptide A as substrate preincubated for 3 hrs followed by substrate ad...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)
Affinity DataIC50:  68nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Broad Institute Of Harvard And Mit

LigandPNGBDBM178100(BRD3308 | US11377423, Cmpd 1)
Affinity DataIC50:  68nMMore data for this Ligand-Target Pair
In DepthDetails US Patent