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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Homeobox protein Brn-2' and Ligand = 'BDBM50149565'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homeobox protein Brn-2


(Homo sapiens (Human))
BDBM50149565
PNG
(4-[(2,2,2-Trifluoro-ethylcarbamoyl)-methoxy]-napht...)
Show SMILES Fc1cccc(NC(=O)c2ccc(OCC(=O)NCC(F)(F)F)c3ccccc23)c1
Show InChI InChI=1S/C21H16F4N2O3/c22-13-4-3-5-14(10-13)27-20(29)17-8-9-18(16-7-2-1-6-15(16)17)30-11-19(28)26-12-21(23,24)25/h1-10H,11-12H2,(H,26,28)(H,27,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.04E+5n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Antagonistic activity against BRN2/DNA interaction by electrophoretic mobility shift assay


Bioorg Med Chem Lett 14: 3875-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.068
BindingDB Entry DOI: 10.7270/Q2ZS2VZW
More data for this
Ligand-Target Pair