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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Homo sapiens phosphodiesterase 2A (PDE2A)' and Ligand = 'BDBM171833'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Homo sapiens phosphodiesterase 2A (PDE2A)


(Homo sapiens (Human))
BDBM171833
PNG
(US9085584, 3)
Show SMILES Cc1ccc2nc(C)c3nnc(-c4cccc(O)c4)n3c2n1
Show InChI InChI=1S/C16H13N5O/c1-9-6-7-13-16(17-9)21-14(10(2)18-13)19-20-15(21)11-4-3-5-12(22)8-11/h3-8,22H,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 155n/an/an/an/an/a25



Boehringer Ingelheim International GmbH

US Patent


Assay Description
For all experiments the Phosphodiesterase [3H]cAMP SPA Enzyme Assay (TRKQ7090, GE Healthcare Europe GmbH) were used. The enzymatic activity of the PD...


US Patent US9085584 (2015)


BindingDB Entry DOI: 10.7270/Q27P8X54
More data for this
Ligand-Target Pair