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Found 2 Enz. Inhib. hit(s) with Target = 'Induced myeloid leukemia cell differentiation protein Mcl-1' and Ligand = 'BDBM31810'
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM31810(Apogossypol derivative, 8r)
Affinity DataIC50:  280nMpH: 7.4 T: 2°CAssay Description:FPAs were performed using various concentrations of GST-Bcl-2 family proteins, incubated with FITC-conjugated peptide substrates in the presence of i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Burnham Institute For Medical Research

LigandPNGBDBM31810(Apogossypol derivative, 8r)
Affinity DataIC50:  330nMAssay Description:Displacement of FITC-labeled Bak BH3 peptide from Mcl-1 after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed