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Found 2 Enz. Inhib. hit(s) with Target = 'Inhibitor of nuclear factor kappa-B kinase subunit beta' and Ligand = 'BDBM50390259'
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Korea University

Curated by ChEMBL
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of IKKbeta using 5FAM-GRHDSGLDSMK-NH2 as substrate incubated for 10 mins prior to substrate addition by IMAP-TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Mus musculus)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of IKKbeta in mouse CIA model spelonocytes assessed as inhibition of TNFalpha production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed