BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Integrin beta-2/Intercellular adhesion molecule-1 /Leukocyte adhesion glycoprotein LFA-1 alpha' and Ligand = 'BDBM50144076'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Integrin beta-2/Intercellular adhesion molecule-1 /Leukocyte adhesion glycoprotein LFA-1 alpha


(Homo sapiens (Human))
BDBM50144076
PNG
((S)-2-(2,6-Dimethyl-benzoylamino)-3-(3H-imidazol-4...)
Show SMILES Cc1cccc(C)c1C(=O)N[C@@H](Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C15H17N3O3/c1-9-4-3-5-10(2)13(9)14(19)18-12(15(20)21)6-11-7-16-8-17-11/h3-5,7-8,12H,6H2,1-2H3,(H,16,17)(H,18,19)(H,20,21)/t12-/m0/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

antibodypedia
antibodypedia
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.77E+3n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibitory activity against association of LFA-1 with intercellular adhesion molecule 1


Bioorg Med Chem Lett 14: 2055-9 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.046
BindingDB Entry DOI: 10.7270/Q2T1532F
More data for this
Ligand-Target Pair