Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Interleukin-1 receptor-associated kinase 4' and Ligand = 'BDBM294305'
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme Corp

US Patent
LigandPNGBDBM294305(US9586948, Example 24)
Show SMILES CNC(=O)c1cccc(c1)-c1cccc(n1)C(=O)Nc1cn(C)nc1C(N)=O
Show InChI InChI=1S/C19H18N6O3/c1-21-18(27)12-6-3-5-11(9-12)13-7-4-8-14(22-13)19(28)23-15-10-25(2)24-16(15)17(20)26/h3-10H,1-2H3,(H2,20,26)(H,21,27)(H,23,28)
Affinity DataIC50: 201nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid