Found 8 Enz. Inhib. hit(s) with Target = 'JAK3/JAK1' and Ligand = 'BDBM50193995' 
Affinity DataIC50: 6.70nMAssay Description:Inhibition of JAK1/JAK3 in human PBMC assessed as reduction in IL2-induced STAT5 phosphorylation pre-incubated for 30 mins before IL2 stimulation for...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 28nMAssay Description:Inhibition of JAK3/1 in human T cells expressing CD3 assessed as inhibition of IL2-stimulated STAT5a phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of JAK1/3 in human PBMC expressing CD3 assessed as inhibition of IL2-induced STAT5a phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-21 induced STAT3 phosphorylation preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-21 induced STAT3 phosphorylation preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of JAK1/JAK3 in human whole blood assessed as inhibition of IL-15-induced STAT-5 phosphorylation preincubated for 45 mins followed by IL-1...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-15 induced STAT5 phosphorylation preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human lymphocytes of whole blood assessed as reduction in IL-15 induced STAT5 phosphorylation preincubat...More data for this Ligand-Target Pair
