Found 7 Enz. Inhib. hit(s) with Target = 'Kappa-type opioid receptor' and Ligand = 'BDBM50002184' TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University
Curated by ChEMBL
Oregon State University
Curated by ChEMBL
Affinity DataKi: 0.0230nMAssay Description:Inhibition of [3H]- bremazocine to opioid receptor kappa of guinea pig cerebral membranes was determinedMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University
Curated by ChEMBL
Oregon State University
Curated by ChEMBL
Affinity DataKi: 0.150nMAssay Description:Compound was tested for binding affinity towards kappa opioid receptor in guinea pig cerebellar membrane using [3H]-bremazocineMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in HEK293 cell membranes by radioligand binding assay relative to controlMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Binding affinity towards Opioid receptor kappa 1 expressed in CHO cells was determined by using [3H]-diprenorphine as radioligandMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University
Curated by ChEMBL
Oregon State University
Curated by ChEMBL
Affinity DataIC50: 0.114nMAssay Description:Binding affinity against Opioid receptor kappa 1 in guinea pig brain homogenate using [3H]- U-69593 as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 2.80nMAssay Description:Agonist activity at mouse KOR expressed in HEK293 cell assessed as inhibition of cAMP concentration incubated for 1 hrs by time-resolved fluorescence...More data for this Ligand-Target Pair
Affinity DataEC50: 116nMAssay Description:Agonist activity at EGFP-tagged mouse KOR expressed in HEK293 cells co-expressing beta-arrestin2 nano-luciferase assessed as beta-arrestin2 recruitme...More data for this Ligand-Target Pair
